The ovary is one of the most powerful—but least understood—organs shaping women’s lifelong health. It serves as the core regulator of women’s brain, immune, heart, metabolic, muscle, and bone health across the lifespan. Despite this profound influence, the medical paradigm remains reactive: we don't routinely measure ovarian function, track its signals over time, or act until a serious condition is already present. Medicine has a critical blind spot, contributing to the fact that women spend 25% more of their lives in poor health compared to men.

For decades, ovarian science has focused almost exclusively on fertility, leaving its critical role in whole-body health largely unexplored. What if ovarian health became a vital sign that unlocks personalized, proactive healthcare supporting every stage of a woman’s life?

The Ovarian Health Prize is a 4-year global moonshot with a $50M prize purse to change the course of women’s health forever. The prize will challenge innovators worldwide to convert invisible signals into breakthroughs for disease prediction and care.

These innovations could mean:

• Smarter care, where women and their doctors can spot early signs of change and protect women’s health before problems arise in the brain, heart, metabolism, or immune systems.
• Everyday tools that help women understand their bodies, stay healthier longer, and make more informed choices about their well-being.
• Breakthrough discoveries that open new frontiers in women’s health, from novel multi-omic biomarkers to next-generation medicines and technologies.

Addressing ovarian health is not only about equity—it’s one of the most powerful and overlooked opportunities for global health and economic growth.

FROM HIDDEN SIGNALS TO PROACTIVE INSIGHTS

A deeper understanding of ovarian signaling pathways and their influence on systemic health will drive earlier detection, proactive care, and personalized, whole-body health.

500 HEALTHY DAYS FOR 3.9 BILLION WOMEN 

Better tools to measure and support ovarian health could help close the gender health gap, and add an average of 500 extra days of healthy life for nearly half the planet.  

$1 TRILLION IN GLOBAL GROWTH

Healthier lives mean stronger economies. Gains in women’s health could unlock up to $1 trillion in annual GDP by 2040 through reduced healthcare costs, increased workforce participation, and expanded productivity.

We’re entering a pivotal moment for women’s health. Now is the time to transform ovarian biology from overlooked to a cornerstone of informed, proactive care. By supporting this moonshot, you will:

• Pioneer tools that make ovarian health measurable 
• Advance equity by closing the women’s health gap 
• Fuel cross-sector innovation in health, biotech, and consumer markets with ovarian-driven insights.

Together, we can transform medicine’s greatest blind spot into a breakthrough for humanity.